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Description

Targeting cGAS/STING signaling-mediated myeloid immune cell dysfunction in TIME

Davern, T

The crosstalk between hepcidin-SLC40A1 mediated system iron metabolism and IRP-IRE regulated cellular iron homeostasis is that the IRP-IRE system senses cellular iron starvation and limits iron losses, whereas hepcidin-FPN protects the organism against systemic iron overload